NEUROENDOCRINE TUMOURS IN PATIENTS OPERATED FOR ACUTE APPENDICITIS: A RETROSPECTIVE CLINICAL STUDY



One-Tube-Only Standardized Site-Directed Mutagenesis: An Alternative Approach to Generate Amino Acid Substitution Collections.

Site-directed mutagenesis (SDM) is a powerful tool to create defined collections of protein variants for experimental and clinical purposes, but effectiveness is compromised when a large number of mutations is required.We present here a one-tube-only standardized SDM approach that generates comprehensive collections of amino acid substitution varia

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